Meeting Place & Times:
EEF 2405
Wednesdays 13.00-16.00

Office Hours: EEF 7205  only by appointment either
by e-mail to cilesiz[at]itu.edu.tr or
by phone to 212 285 67 73

 

BYM504E Biomedical Imaging Systems (CRN: 23514)

Grading: Simulation/Assignments 20%; Midterm Exam 20%; Project 20%; Final Exam 40%

Midterm Exam:

tentatively 9th week of classes

Imaging Simulation due:

tentatively after the BREAK (26-30 March 2018)

Project Presentations:

9 and 16 May 2018

Final Exam:

TBA

 

There IS a NINOVA page for this course!

 

Course Objective: 

 

This course will provide a detailed review of imaging principles and instrumentation of all the conventional clinical imaging systems, including X-ray radiography, computerized tomography (CT), gamma camera, SPECT, PET, ultrasound (US), Doppler US, Magnetic Resonance (MR) and functional MR (f-MR).
 

Course Description:
 

• General characteristics of imaging systems;
• X-ray and CT: general principles, interaction of X-rays with tissues, contrast agents, imaging techniques, image reconstruction, radiation dose;
• Nuclear Medicine: general principles, radionuclide, radioactive decay, gamma camera, imaging techniques, SPECT, PET;
• Ultrasound imaging: general principles, interaction of acoustic waves with tissue, acoustic impedance, instrumentation, scanning modes, artifacts, blood velocity measurements, contrast agents;
• MR imaging: general principles, nuclear magnetism, magnetic resonance, instrumentation, imaging sequences, contrast agents, imaging techniques, functional MRI.
 

Participation/Assignments: 

 

• As part of in class participation each student will have to do several oral and/or written presentations on topics assigned by the instructor.
• Each student will simulate an imaging modality (such as, CT or US) using a tissue phantom of his/her choice and will present the results with a demonstration and in laboratory report format.
• An in depth review on an imaging modality/system not covered in class. Results of this literature/lab or clinical study review will be presented orally in class and in writing in report format.
 

Course Plan:

 

 

Weeks

 

Topics

1

Introduction to biomedical imaging

2

General image characteristics

3

X-rays, X-ray film, instrumentation

4

CT, instrumentation, Fourier slice theorem, image reconstruction

5

Nuclear medicine, radioactivity, technetium generator, use of technetium

6

Gamma camera, SPECT, PET, instrumentation

7

Image reconstruction, clinical applications

8

Ultrasound, wave propagation and acoustic impedance, instrumentation

9

Midterm exam

10

US imaging characteristics, scanning methods and modes, Doppler US

11

MR imaging, magnetic resonance, Larmor frequency, relaxation

12

Slice selection, phase/frequency encoding, imaging sequences, functional MRI

13

Project presentations

14

Project presentations

 

Textbooks: 

 Introduction to Medical Imaging: Physics, Engineering and Clinical Applications, Nadine B. Smith & Andrew Webb, Cambridge University Press, 2011, ISBN-13: 978-0521190657. (shown on the left!)

Other reference books:

Biomedical Imaging: Principles and Applications, Editor: Reiner Salzer, John Wiley & Sons, Inc., 2012 , Online ISBN: 9781118271933.
 The Chemistry of Molecular Imaging, Editors: Nicholas Long, Wing-Tak Wong, John Wiley & Sons, Inc., 2015, Online ISBN: 9781118854754. 
Advances in Optical Imaging for Clinical Medicine, Editor(s): Nicusor Iftimia, William R. Brugge, Daniel X. Hammer, John Wiley & Sons, Inc., 2011, Online ISBN: 9780470767061.

Do not FORGET to check out this link. You need to have online access to library resources to read this handbook.
That also means you need to check out online library resources such as Knovel E-Kitap and CRC ENGnetBASE.
 


Project:
 

 

involves an in depth review on one of the newer biomedical imaging modalities not covered in class...

if available: principles, instrumentation on the market, along with price and maintenance are to be covered in a 15-20 minute in-class oral presentation on the last two weeks of class AND an accompanying 10 page maximum word-processed report.

Reports without (i) identification of its author, (ii) a reference list, and (iii) numerous spelling errors (please run spell-check) lead to "reduced" grades. Mot-a-mot copied (i.e., copy/paste) reports are not favored! For information on how to write an effective report and make an effective presentation consult "Scientific and Technical Writing" lectures notes.
 

Suggested Topics:

  • new frontiers in Optical Coherence Tomography
  • new frontiers in opto-acoustic/deep tissue Imaging
  • 3-d Optical Projection Tomography
  • Optical Metabolic Imaging
  • T-ray Imaging
  • Magnetic Field Correlation MR Imaging
  • DNP-enhanced MRI (DNP = Dynamic Nuclear Polarization)
  • Near-infrared fluorescence imaging (with or without biomarkers)
  • Endoscopic multispectral imaging
  • Hybrid imaging
  • Dual imaging
  • Fusion imaging

ANYTHING ELSE NOT COVERED IN CLASS, but INTERESTING TO YOU.

Other topics may be found in the online books under CRC ENGNETBASE and WILEY e-BOOKS available from ITU library on and off-site using your ID.

Interesting Links:

Human Connectome Project  (see and click on the images on the left!)
Micro CT

Dental MicroCT

Overview of Imaging Tests
 Modern Imaging Techniques
 Physics and Technology of Medical Imaging
Introduction to Ultrasonic Testing

Medical Imaging News

Medical Imaging Modalities

 

For more info on class visit previous years' web sites in the archives...